tag:blogger.com,1999:blog-7857054149675424609.post1197413409247164156..comments2024-02-24T08:58:08.581+00:00Comments on RNAi Therapeutics: RXi Reports Dose-Related Knockdown Three Months Following Single InjectionDirk Hausseckerhttp://www.blogger.com/profile/18320439857875629714noreply@blogger.comBlogger10125tag:blogger.com,1999:blog-7857054149675424609.post-3561967432055626662013-06-15T10:09:25.037+00:002013-06-15T10:09:25.037+00:00Myriad Supreme decision...it's an interesting ...Myriad Supreme decision...it's an interesting thought whether it affects RNAi Rx. However, since the IP coming closest to the Myriad issue in the space concerns patents that protect RNAi triggers directed at genes, and not the genes themselves, I do not see the ruling to change much here. The ruling does, however, make it less likely that you can discover a gene, including the new class of Dirk Hausseckerhttps://www.blogger.com/profile/18320439857875629714noreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-4145957683747422922013-06-15T01:53:04.379+00:002013-06-15T01:53:04.379+00:00The scarce resource now is silencing the genes in ...The scarce resource now is silencing the genes in the most effective way. Viral and human genes are now plentiful since nobody can own them.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-4096363291455490112013-06-15T01:23:18.504+00:002013-06-15T01:23:18.504+00:00Dirk,
You should write an entry about how the Supr...Dirk,<br />You should write an entry about how the Supreme Court's decision that genes in their natural state cannot be patented actually makes RNAi drug delivery technologies even more valuable since value shifts from owning genes to creating the best drug to silence them.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-54882192177772081042013-06-12T00:48:40.296+00:002013-06-12T00:48:40.296+00:00Yeap. The RAC acknowledged that the latest HCV dru...Yeap. The RAC acknowledged that the latest HCV drugs will be big improvement but there was still a real need for a one shot HCV treatment because in many countries it won't be possible to ensure that patients get all the course of treatment required for the oral regimes. This is an endorsement of Benitec's reasoning. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-58976410866867855172013-06-11T23:41:40.455+00:002013-06-11T23:41:40.455+00:00"I am afraid that times for HCV gene therapy ..."I am afraid that times for HCV gene therapy are over".<br /><br />Sounds like they are just beginning to me. RAC unanimously (17/0) endorsed TT-034 and there was much hope and excitment in the room for a one-shot treatment. Benitec, despite it's miniscule share price, just may be the first RNAi company to have a product in commercialisation.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-81759227474942472462013-06-08T20:14:08.812+00:002013-06-08T20:14:08.812+00:00Dirk, what do think of the research Benitec has co...Dirk, what do think of the research Benitec has completed with Medistem combining ddRNAi with adult stem cells over the past few years? I think they investigated rheumatoid arthritis and tissue rejection after transplantation.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-35785499939555617952013-06-08T18:41:49.033+00:002013-06-08T18:41:49.033+00:00Benitec raise...probably the best they could do an...Benitec raise...probably the best they could do and looks fair to small investors. On the other hand, I am afraid that times for HCV gene therapy are over and how do you deliver plasmids to lung cancer cells? It's hard enough to delivery siRNAs to cytoplasm, but large DNA to nucleus of sufficient cells with polymers??Dirk Hausseckerhttps://www.blogger.com/profile/18320439857875629714noreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-24582410994368932732013-06-07T18:33:52.183+00:002013-06-07T18:33:52.183+00:00Ian Ross is at Benitec.need we say more?Ian Ross is at Benitec.need we say more?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-24971091639400441552013-06-06T21:02:13.520+00:002013-06-06T21:02:13.520+00:00What do you think of Benitec's recent $7 milli...What do you think of Benitec's recent $7 million placement to fund HCV and lung cancer trials?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-12330103050281264642013-06-06T15:02:56.057+00:002013-06-06T15:02:56.057+00:00
dirk, why did you illustrate this post with a hor...<br />dirk, why did you illustrate this post with a horrible scar? My immediate response was very negative because I associated the scar with the RXi study. If you had included a faint scar as an illustration of what RXi is trying to accomplish, it would have been better, but no illustration would have been best.Anonymousnoreply@blogger.com