tag:blogger.com,1999:blog-7857054149675424609.post297572402449996050..comments2024-02-24T08:58:08.581+00:00Comments on RNAi Therapeutics: Santaris Terminates PCSK9 Hypercholesterolemia TrialDirk Hausseckerhttp://www.blogger.com/profile/18320439857875629714noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-7857054149675424609.post-65721367265613082202013-07-12T10:37:14.160+00:002013-07-12T10:37:14.160+00:00I appreciate all of the information that you have ...I appreciate all of the information that you have shared. Thank you for the hard work!<br /><a href="http://www.enzymatics.com/product_rnase-inhibitor.htm" rel="nofollow">rnase inhibitor</a> is an acidic, 52 kDa protein that is a potent non-competitive inhibitor of pancreatic-type ribonucleases such as RNase A, RNase B, and RNase C. Anonymoushttps://www.blogger.com/profile/01418402263179550192noreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-31131338375411580542011-10-09T05:45:44.461+00:002011-10-09T05:45:44.461+00:00Dirk man it would be ausome if your treatment of c...Dirk man it would be ausome if your treatment of certain companies would be a little more unbiased.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-64161517684775656182011-10-07T16:20:09.062+00:002011-10-07T16:20:09.062+00:00Not sure about the fate of the tt-034 compound. T...Not sure about the fate of the tt-034 compound. The glacial pace with which this compound seems to move could be a bit worrisome. I don't see Pfizer spearheading DNA-directed RNAi Therapeutics.<br /><br /><br />"Lastly, I would assume you would consider Isis' intrathecal delivery for neurodegenerative diseases as a local application"<br /><br />I was thinking about exactly Dirk Hausseckerhttps://www.blogger.com/profile/18320439857875629714noreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-1568803253556673592011-10-07T14:14:35.971+00:002011-10-07T14:14:35.971+00:00As an investor in both antisense and RNAi I have g...As an investor in both antisense and RNAi I have greatly appreciated your insight, particularly with respect to the pros and cons of both approaches.<br /><br />Any prudent investor should be seeking out the most knowledgeable, unbiased and up-to-date information regarding the cumulative safety database for each approach.<br /><br />I agree 100% with your last paragraph that now, finally, with Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-35099241665612211652011-10-07T13:30:20.870+00:002011-10-07T13:30:20.870+00:00Dirk, any word on the street as to when or if pfiz...Dirk, any word on the street as to when or if pfizer will commence P1 trial of the tt-033 compound?Anonymousnoreply@blogger.com