tag:blogger.com,1999:blog-7857054149675424609.post3609488190742589819..comments2024-02-24T08:58:08.581+00:00Comments on RNAi Therapeutics: FDA Greenlights Use of TKM-EBOLA in Current OutbreakDirk Hausseckerhttp://www.blogger.com/profile/18320439857875629714noreply@blogger.comBlogger11125tag:blogger.com,1999:blog-7857054149675424609.post-82905697941279587442014-10-20T21:14:49.564+00:002014-10-20T21:14:49.564+00:00BLT will never be a success story as things stand ...BLT will never be a success story as things stand or by itself. <br /><br />When you read that article Dirk posted up, it is clear, the vision of the two main men in BLT is to make a wad of cash and go home. Sounds like a trade sale to me.<br /><br />There is no mention of the new lab and apparently the toxicity issues of old are still unresolved due to the high number of "events" in Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-12963383945233106772014-10-18T08:33:25.150+00:002014-10-18T08:33:25.150+00:00It's not like this is the first time this has ...It's not like this is the first time this has ever happened...<br />Does this mean BLT will become a success story?<br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-76016815895668811802014-08-12T13:45:57.774+00:002014-08-12T13:45:57.774+00:00Very true. a bit hasty. May do well temporarily ...Very true. a bit hasty. May do well temporarily for the stock price. Hopefully, the cytokine storm issue led to FDA hold does not result in detrimental effect to set the RNAi field back again.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-24553170001792396822014-08-11T21:25:05.343+00:002014-08-11T21:25:05.343+00:00Most likely outcome, share price aside, is new mu...Most likely outcome, share price aside, is new mutant strain of experimental drug resistant Ebola.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-47923784887350194822014-08-11T19:53:22.916+00:002014-08-11T19:53:22.916+00:00http://www.bloomberg.com/news/2014-08-10/new-ebola...http://www.bloomberg.com/news/2014-08-10/new-ebola-drugs-create-debate-over-effects-on-outbreak.html<br /><br />Sierra Leone has contacted Tekmira...Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-39826377389772254322014-08-11T08:13:38.564+00:002014-08-11T08:13:38.564+00:00I think it will another stars day to shine this we...I think it will another stars day to shine this week. Maybe tomorrow.<br /><br />Alnylam is a big constellation.<br /><br />Pity I can't find anything on a Google search that describes it except as a pharmaceutical company.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-32668437533752503072014-08-10T05:49:10.199+00:002014-08-10T05:49:10.199+00:00How do we track the current effectiveness if TKMR-...How do we track the current effectiveness if TKMR-Ebola is used more widely in the current outbreak?Rogerhttps://www.blogger.com/profile/16299399184423150026noreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-84744097076117076102014-08-09T12:31:00.876+00:002014-08-09T12:31:00.876+00:00If tkm ebola works well and it probably will it wi...If tkm ebola works well and it probably will it will leap frog rnai into the viral space, remember the current flu vaccine programs are very lax in there testing as a matter of history, this could achieve the same advantage for rnai. It is interesting that shrna also is close to clinical verification with callimmune HIV and BlT HepC, exciting times indeed.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-23206997798830169772014-08-08T18:06:22.693+00:002014-08-08T18:06:22.693+00:00The Pfizer/Nigeria situation was (at least per tha...The Pfizer/Nigeria situation was (at least per that article) different in that people weren't informed. <br />In this case it's not likely TKM-Ebola will be used without the explicit permission of every stakeholder. <br />That said, the day's (+40%) gains of $TKMR over this news appears to be a bit nonsensical. The results of such a trial aren't likely to meaningfully contribute Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-39686437891869035952014-08-08T13:23:14.414+00:002014-08-08T13:23:14.414+00:00It's not like this is the first time this has ...It's not like this is the first time this has ever happened... for all those who are bullish about use of experimental medicine in africa, here is a cautionary tale<br /><br />http://www.washingtonpost.com/wp-dyn/content/article/2006/05/06/AR2006050601338.html<br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-76154929348543316142014-08-08T10:52:53.778+00:002014-08-08T10:52:53.778+00:00Does this mean BLT will become a success story? Cu...Does this mean BLT will become a success story? Curing Ebola with one shot is quite something.Anonymousnoreply@blogger.com