tag:blogger.com,1999:blog-7857054149675424609.post5994206911327278329..comments2024-02-24T08:58:08.581+00:00Comments on RNAi Therapeutics: Tekmira Ebola Candidate Halted as Disease Spreads in Western AfricaDirk Hausseckerhttp://www.blogger.com/profile/18320439857875629714noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-7857054149675424609.post-37705459905720697342014-07-08T06:47:26.494+00:002014-07-08T06:47:26.494+00:00Pardon me, but wasn't the study done in healt...Pardon me, but wasn't the study done in healthy patients? Therefore, there was no "virally induced" cytokine storm, but is due to the presence ofxenobiotic material. Then again, whether cytokine stimulation will have any good/bad effects remain to be seen. This was discussed in the 2010 article. And isn't the MOA of rnai fairly well understood? Does the immune system play Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-66452539517571593762014-07-06T07:55:27.206+00:002014-07-06T07:55:27.206+00:00Is RGLS the proprietary holder of ssRNAI? Sounds l...Is RGLS the proprietary holder of ssRNAI? Sounds like that's what previous poster is saying.<br /><br />Dirk, I'm sure you've said ssRNAi is proprietary to RGLS. Is this true?<br /><br />If anyone will know it will be you.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-2656567459451104062014-07-06T03:10:20.320+00:002014-07-06T03:10:20.320+00:00Don't be so quick to write off BLT. They'r...Don't be so quick to write off BLT. They're in trials now and will be able to put Dirk's "no lab" issues to bed once n for all very soon.<br /><br />I think previous poster is wrong about ISIS developing ssRNAi. That's what RGLS was set up for.<br /><br />Wouldn't be surprised if BLT buys them out same way they did Tacere.lolAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-20369212085268545462014-07-05T06:10:25.410+00:002014-07-05T06:10:25.410+00:00Where does that leave ssRNAi? Maybe it really is &...Where does that leave ssRNAi? Maybe it really is "da bomb"<br />Dirk, I know you've spoken highly of ssRNAi previously, and of ISIS. Now you're saying TKMR is a no go except if you're long.<br />Does that mean ISIS is a buy in your opinion? Or ALNY because they're about to deal with ISIS and you're on their payroll.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-58938170567095833802014-07-05T05:15:42.038+00:002014-07-05T05:15:42.038+00:00A little while ago the CEO of BLT made a presentat...A little while ago the CEO of BLT made a presentation to AZ selling their wares. In it, it was stated their ddRNAi technology was being used by Tekmira along with several others.<br />Now TKMR's Ebola program gets halted.<br />Not a good look for TKMR. Or BLT. Or any of the other companies named in the AZ presentation. And kind of rings the death knell for ddRNAi as a platform technology.<br Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-7857054149675424609.post-18544363052473976102014-07-04T14:52:08.912+00:002014-07-04T14:52:08.912+00:00As always much appreciated that you continue to ed...As always much appreciated that you continue to educate.. keep up the great work dirk.Anonymousnoreply@blogger.com