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Showing posts with label TTR. Show all posts
Showing posts with label TTR. Show all posts
Sunday, January 7, 2018

Going into 2018, OligoRx Has Become Mainstream Drug Modality

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When I became interested in drug development almost 2 decades ago, I just didn’t get it: why was it that gene-centric biotech was seen as ...
2 comments:
Wednesday, April 22, 2015

First RNAi Therapeutic Nearing Finish Line

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ALN-TTR02 for the treatment of TTR amyloidosis is the most advanced RNAi Therapeutic in clinical development and has been carrying the tor...
7 comments:
Friday, November 14, 2014

Injection Site Reactions and Liver Toxicity Emerge as Major Issues for GalNAc-siRNA Technology

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Alnylam this morning reported top-line results from a phase II study of their first clinical candidate based on the GalNAc-siRNA conjugat...
15 comments:
Sunday, November 20, 2011

Phase I Study of ALN-TTR01 in Transthyretin Amyloidosis- A Preview

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( For a discussion of the phase I results, see here ). Alnylam is about to reveal results from its phase I study with ALN-TTR01 for the tr...
4 comments:
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